PANEL: Comparing Traditional Methods for Aggregation Analysis & Effective Safety Profiling
Time: 12:00 pm
day: Day One AM - B
Details:
- Comparing DLS, vs Size Exclusion Chromatography vs Asymmetrical Flow Field-Flow Fractionation to determine orthologous methods that can be used to increase the accuracy of profiling aggregates
- Using aggregation analytical tools to determine whether empty or full capsids more prone to aggregation
- Discussing the regulatory expectations on aggregation to inform what areas of aggregation formation should have mitigation strategies imposed
